The body naturally makes three estrogen hormones; estradiol, estrone, and estriol. These estrogens are powerful hormones that play a chief role in regulating fat deposition and fat burning. Estrogens cause fat to accumulate, especially around the hips, thighs and abdomen.
Central obesity, or 'apple shaped' weight gain greatly increases the risk of diseases such as insulin resistance, type 2 diabetes, even cancer.
Identifying estrogen dominance may be the key to losing weight and keeping it off.
Estrogens also play a primary role in regulating weight gain in men. An increase in body fat is associated with greater activity of the aromatase enzyme that irreversibly converts testosterone to estrogen, leading to diminished testosterone levels.
Too much aromatase activity favours the preferential deposition of fat around the belly and chest.
Belly fat and gynecomastia (benign enlargement of the male breast) is a strong indicator of estrogen dominance in a man. This type of weight gain signals too little free testosterone and too much estrogen.
Central weight gain in men greatly increases the risk of obesity related diseases.
Calcium D-glucarate is a natural compound that aids the detoxification of estrogen. It not only inhibits b-glucuronidase, the enzyme that allows re-absorption of estrogen in the digestive tract, it also increases the activity of the specific liver pathway that assists elimination of estrogens.
Bioavailable Diindolylmethane (DIM) is a phytochemical naturally derived from cruciferous vegetables such as broccoli. Research shows that bioavailable DIM has a powerful effect on estrogen metabolism. The key action of bioavailable DIM is in assisting the clearance of available estrogen via the healthy pathway.
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